Organization: Bhabha Atomic Research Centre, India. Work: Isolation of environmental bacteriophages for anti-biofilm activity. Characterization of marine and freshwater bacteriophages against pathogenic bacterial strains for their therapeutic applications and combating multidrug-resistant bacterial strains. Searching the genome of marine and freshwater bacteriophages for the presence of novel metabolic pathways.
Skills & Expertise
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Microbial fouling in water treatment plants
Microbial fouling poses serious problems in cooling circuits, wherein they reduce heat transfer efficiency resulting in a significant pressure drop in the condensers as well as impairing the performance of associated ancillary systems. Predicting the type, rate, and extent of microfouling phenomena manifests the problem of biofouling in industrial cooling systems and affects the operation of industrial equipment which is prone to biofouling. Microbes thrive in the conducive environment of cooling water systems which aids in adhesion and growth. The colonized microbes and their metabolic products can deteriorate the various material of the cooling circuit. The microbial consortia are also implicated in the corrosion phenomenon since they are locally focused on the metal surfaces. The degree of colonization on the metallic surfaces by microfouling bacteria is distinct; this aids in generating corrosion potentials as large as that generated between incompatible metals.
Biofilm extracellular polymeric substances-based bioremediation of radionuclides
There have been consistent efforts to develop bioremediation technologies for radionuclides for the treatment of mildly active radioactive wastes or radionuclides contaminated waters. Most of radionuclides of concern are heavy metals (U, Pu, Th, Sr, etc.), which cannot be degraded. These radionuclides can be precipitated, concentrated, or immobilized to reduce their hazardous nature. Microbial biofilms have been identified as an emerging potential technology for bioremediation of many hazardous and toxic pollutants, such as heavy metals, dyes, poly-aromatic hydrocarbons, etc. In this chapter, we focus on how microbial biofilms and extracellular polymeric substances of biofilms can be of use to develop technologies for the bioremediation of radionuclides. This chapter further attempts to provide an insight into major mechanisms involved in mitigation of radionuclides and the challenges pertinent to potential bioremediation using microbial biofilms.
Nanobiosensors for virus detection in the environment
Since, humans are the most sensitive and valuable host to viruses, their detection at an early stage is of utmost importance to save a life. Up to now, many assays have been developed which can detect the presence of virus in cells and body fluids, but most of them are time consuming and non-feasible processes. To minimize the work load and time consumption, nano-sensors are developed which are based on utilization of biological components. These sensors use biological outfits like enzyme of a reaction, ligand of any receptor or fluorescent signals developed in any kind of reactions. Possibility of any of the above process in any kind of viral infected system leads to generation of signals which is further processed and amplified to confirm the presence of viral particles. Nano biosensors are preferred over other assays because they are handy, multiple application and minimum time consuming.
Biopesticides: Current Status and Future Prospects in India
Though the chemical pesticides are very effective, what concerns over their use is their effect on soil and environment and presence of residue in food products. Another major issue is the development of resistance in the pests. Therefore, the use of biopesticides to control pests is now preferred over synthetic pesticides because of their pest control ability and diverse mode of actions which helps in avoiding resistance development in the pests. In a country like India with a huge diversity of plants, there is an urgent need for identifying new biopesticides which can serve the purpose of pest control. India needs to develop its own biocontrol agents (BCA) because it will be cost-effective and also environment-friendly. Major hurdle in the development and use of new biopesticides in India is the commercialization process. The farmers are reluctant to use the new products because of high cost and no practical knowledge.
Molecular Evolution of Xenobiotic Degrading Genes and Mobile DNA Elements in Soil Bacteria
When the contaminants started effecting human health, man started utilizing these organisms for the biodegradation of toxicants. For example, in the past few decades, the organisms which were present in the environment and deliberately confronting discrete precarious chemical pollutants have emerged with the potential to degrade them. The microorganisms have emerged successfully to grow in presence of xenobiotics and began using them as their carbon source. Later, the role of certain mobile DNA elements which are detailed in this chapter revealed that by conjugating with the other aromatic degrading bacterial catabolic genes as transposable elements, the xenobiotics were efficiently mineralized. Evolutionary indications suggest that microbes have also evolved certain metabolic pathways by transposition of new catabolic genes into their genome for xenobiotic degradation
World Society for VirologyFull Time
April 2021 - Present
Al Hawiyah, Taif Saudi Arabia
World Society for Virology was established to strengthen collaboration of virologists worldwide without restriction. The WSV main mission is to strengthen virology research to different viral diseases of humans, animals, and plants. World Society for Virology main objectives include but not limited to: Build up a network of scientific collaboration among virologists worldwide. Build international bridges for virology laboratories worldwide.
Antibiotic Resistance-India-IIMARFull Time
July 2020 - Present
Vellore , Tamil Nadu India
IIMAR was formed in MARCH 2008 to promote prudent use of antibiotics so as to reduce the possibility of spread of antibiotic resistance. Coordinators: Dr. A. J. Tamhankar & Dr. Mira Shiva. Let us all JOIN together and spread a word for prudent use of antibiotics.Dr.Ramesh Nachimuthu currently serving as a Joint Coordinator-IIMAR. Organization- Non financial. No membership fee. No funds. Operates and sustains on members own initiatives and funds. Every member aware about AMR. Makes others aware about AMR. Every volunteer worker works in his /her own comfort space. Every volunteer leader is a coordinator at his/her own niche/Environment.
Society for Bacteriophage Research and TherapyFull Time
July 2020 - Present
Varanasi, Uttar Pradesh India
The society is intended to work together as a team for the betterment of bacteriophages and its positive global impact on the society. But, our concern can only be perfected when the scientists and clinicians working in different areas of basic and translation research in different aspects of bacteriophages are coming altogether on a single platform. Therefore, this society has been evolved to have a platform where researchers working in different areas of bacteriophages e.g. water bodies especially in rivers; clinical application of phages i.e. as antibacterial, vaccines, gene therapy, diagnostics, drug delivery, cancer therapy; water and sewage treatment, animal husbandry, poultry, food safety, aquaculture, agriculture, industry etc. may exchange and share the knowledge and facility altogether at national level. This is high time for you to consider joining hands for a noble cause.
International Society for Viruses of MicroorganismsFull Time
July 2020 - Present
Leicister, England UK
The ISVM is a professional society that connects people working with viruses that infect microorganisms like bacteria, fungi, algae, archaea, and protists. Because tiny things are hugely cool.
International Bacteriophage Research ConsortiumFull Time
April 2019 - Present
New Delhi, New Delhi India
The purpose of this group is to create awareness on bacteriophage research and therapy for managing antimicrobial resistance (AMR) and to promote and expand the International Bacteriophage Research Consortium (IBRC), a joint endeavour of ANDC, DU & OHSL, USA.
Bhabha Atomic Research CentreFull Time
August 2016 - Present
Chengalpattu, Tamil Nadu India
The Bhabha Atomic Research Centre is India's premier nuclear research facility based in Tarapur and Trombay, Mumbai, Maharashtra. BARC is a multi-disciplinary research centre with extensive infrastructure for advanced research and development covering the entire spectrum of nuclear science, engineering and related areas.BARC's core mandate is to sustain peaceful applications of nuclear energy, primarily for power generation. It manages all facts of nuclear power generation, from theoretical design of reactors, computerised modelling and simulation, risk analysis, development and testing of new reactor fuel materials, etc.
Homi Bhabha National Institute
PG Diploma in Nuclear Science
2015 - 2016
School of Biotechnology, Banaras Hindu University
Master of Science in Biotechnology
2013 - 2015
Department of Zoology, Banaras Hindu University
B.Sc. (Hons.) Zoology
2010 - 2013